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Prevent concomitant usage of tucatinib with CYP3A substrates, wherever minimal concentration modifications could bring about major or life-threatening toxicities. If unavoidable, reduce CYP3A substrate dose Based on item labeling.Stiripentol is often a CYP3A4 inhibitor and inducer. Keep track of CYP3A4 substrates coadministered with stiripentol for